Proactive health intelligence
Annual physicals don't paint a complete picture. Circle is built for earlier detection and supported prevention.

Diagnostic testing at Circle
Biomarker testing is the foundation of longevity. Our panels show you how your systems are functioning, how they interact, and how those patterns change over time. An ongoing view of your health helps you can act early and prevent issues before they start.
Our approach
The Circle approach to testing
We test what matters
Testing is never ordered in isolation or as part of a checklist. We only test what will actually guide your care and impact your real life.
We look for patterns, not flags
We examine all results, optimal and sub-optimal, alongside other markers, symptoms, and trends to understand whether they're meaningful.
We pay attention to trends
Single data points don't tell your whole health story. The real insights appear in tracking health changes over time.
We interpret everything in context
Age, lifestyle, medications, stress, sleep, and goals matter just as much as biomarkers. Your results account for your whole health.
Every test comes with guidance
Your results don't arrive as raw numbers. Every test includes a physician review so you understand what your biomarkers mean, what's changed, and what to do next.
- Clinician interpretation by a physician
- Clear explanation of what matters most for you
- Recommended areas for improvement
- Actionable next steps, if applicable
- Results added to your health record and Circle dashboard

Foundational biomarker testing
Core biomarker panel
Included in Circle Core membership or $[price TBD] per panel for non-members.
The Core biomarker panel establishes a baseline understanding of your overall health, including inflammation, metabolism, cardiovascular risk, nutrient status, and organ function.
This panel is designed to:
- Detect early changes before symptoms escalate
- Identify areas for improvement
- Establish a clear view of your health over time
Biomarkers included in this panel
This panel tests 60+ core biomarkers. Any sub-optimal markers are re-tested semi-annually.
Cardiometabolic health
Total cholesterol, LDL, HDL, non-HDL cholesterol, triglycerides, cholesterol/HDL ratio, Apolipoprotein B (ApoB), Lipoprotein (a), hs-CRP, Fasting glucose
Blood + cellular health
Complete blood count indices including hemoglobin, hematocrit, red blood cell count, platelet count, MCV, MCH, MCHC, RDW, MPV
Inflammation
hs-CRP
Thyroid function
Thyroid-stimulating hormone (TSH), Free T4, free testosterone (male only)
Expanded biomarker panel
$[price TBD] per panel.
Expanded biomarker panels examine hormonal balance, cardiometabolic risk, and longevity-relevant markers for those seeking deeper insight.
These panels are used strategically when the additional information will purposefully guide care.
Biomarkers included in this panel
This panel tests 100+ biomarkers, with semi-annual repeat testing. Any sub-optimal markers are re-tested quarterly.
Heart + vascular health
Total cholesterol, LDL, HDL, non-HDL cholesterol, triglycerides, cholesterol/HDL ratio, Apolipoprotein B (ApoB), Lipoprotein (a), high-sensitivity C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR)
Cardiovascular age + risk
Cardiovascular risk context derived from validated clinical models and interpreted alongside expanded biomarker data
Biological age
Advanced biological age assessment with deeper longitudinal trend interpretation
Metabolic health + insulin dynamics
Fasting glucose, Hemoglobin A1c (HbA1c), fasting insulin, C-peptide, uric acid, insulin resistance indices (e.g., HOMA-IR)
Earlier insights, ongoing support
No more “everything looks normal.” See all your results as optimal or sub-optimal based on average ranges for your age and biological sex.
And we'll help you understand what they mean within the context of your history, current lifestyle, and future goals.
Biological Age
7.6 yrs younger
Book your panel“Where is your health heading and how do we improve your trajectory?”
Additional Diagnostics
Specific health concern? On-demand diagnostic testing offers a deeper understanding of key health areas including cancer and genetic risk, hormone health, and more.
Coming soon
Test 1
Brief description
Coming soon
Test 2
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Coming soon
Test 3
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Coming soon
Test 4
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Coming soon
Test 5
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Coming soon
Test 6
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Cancerguard® multi-cancer detection
Cancerguard® is a simple blood test that helps detect over 50 cancer types and subtypes even before symptoms appear.
As a multi-cancer early detection (MCED) test, Cancerguard® complements traditional screenings by looking for signals across multiple cancer types at once.
Speak to your Circle team about Cancerguard® if:
- You want peace of mind
- You have increased risk factors for cancer
- You're 3+ years post a cancer diagnosis
- You have a family history of cancer
